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Table 1 Briefly describes all the three cases of primary pilocytic astrocytoma of cerebellopontine angle in pediatric population

From: Primary pilocytic astrocytoma of cerebello-pontine angle in the pediatric age group: literature review and case report

 

Age/sex

Clinical presentation

Duration in months

Size

Site of origin

Histo-morphology

IHC

WHO grade

Arnautovic et al. [4]

9/F

Headache, vomiting, decreased sensation in right half of face, mild facial weakness

2

3:5 × 4 × 4:5 cm

CN V

Pilocytic astrocytoma

No

No

Mirone et al. [5]

12/M

Impaired hearing, headache

36

2.18 × 2.23 × 2.37 cm

CN VIII

Pilocytic astrocytoma

GFAP + 

No

Reticulin − 

S-100 − 

Zakaria et al. [6]

14/M

Occipital headache, blurring of vision, impaired hearing

0.5

3.5 × 3.5 × 2.5 cm

CN VIII

Pilocytic astrocytoma

GFAP + 

1

P53 − 

Ki67 < 1%

Our case

11/M

Impaired hearing, headache, vomiting

4

5.0 × 4.3 × 5.0 cm

CN VIII

Pilocytic astrocytoma

GFAP + 

1

IDH − 

ATRX retained

P53 wild type

Ki67 2%

  1. Although the histomorphology in this case is the same as the previous cases, the immunohistochemical analysis and WHO grading were done according to the latest guidelines. [CN: cranial nerve, GFAP: Glial fibrillary acidic protein, IDH: Isocitrate dehydrogenase, ATRX: α-thalassemia mental retardation X-linked protein]