Table 1 Evidence of decompressive craniectomy in traumatic brain injury: a summary of the outcomes
Study | Country | Population | Outcome | ICP levels |
|---|---|---|---|---|
Taylor et al. [69] | Australia | N = 27 Age (13.6–176.4 Months) | Favorable Functional Outcome (GOS > 5) Decompressive Craniectomy group 54% Control group 14% | Decompressive Craniectomy 17.4 ± 3.4 mm Hg Control 21.9 ± 8.5 mm Hg |
Qiu et al. [71] | China | N= 74 Age (18–65 years old) | Favorable Functional Outcome (GOS > 5) Decompressive Craniectomy group 56.7% Control group 32.43% Mortality Decompressive Craniectomy group 27% Control group 57% | Decompressive Craniectomy 15.98 ± 2.24 mm Hg Control 21.05 ± 2.23 mm Hg |
Cooper et al. [72] | Australia New Zeland Saudi Arabian | N = 15 Age (15–59 years old) | Unfavorable Functional Outcome (GOS < 5) Decompressive Craniectomy (51%) versus Control (42%) OR 2.21 (95% CI 1.14–4.26, p = 0.02) | Decompressive Craniectomy 14.4 ± 6.8 mm Hg Control 19.1 ± 8.9 mm Hg |
RESCUEicp Trial [73] | 23 Countries | N = 408 Age (10–65 years old) | Unfavorable Functional Outcome (GOS < 5) At 6 Months Decompressive Craniectomy 72% (146/202) versus Control 70.4% (138/196) At 12 Months Decompressive Craniectomy 68% (132/194) versus Control 79.32% (142/179) | Decompressive Craniectomy 14.5 (1.7–18) mm Hg Control 17.1 (4.2–21.8) mm Hg |
DECRA Study [74] | 10 Countries | N = 155 Age (18.5–34.9 years old) | Mortality OR 1.58 (95% CI 0.84–2.99; p = 0.16) Vegetative state at 6 Months OR 5.85 (95% CI 1.21–28.30; p = 0.03) Severe disability at 6 Months OR 2.49 (95% CI 1.21–5.11; p = 0.01) | No reported |