Role of intra-discal Vancomycin instillation in prevention post-operative discitis

Egyptian Journal of Neurosurgery

Table 2 Operative and post operative data of the studied groups

Variable	Group I	Group II	t	P
Variable	Vancomycin (n = 50)	No vancomycin (n = 50)	t	P
Operation time
Mean ± SD	85.5 ± 9.02	87.08 ± 9.61	0.85	0.40
Range	70–106	70–110		NS
Blood loss
Mean ± SD	80.22 ± 26.94	78.68 ± 29.14	0.27	0.78
Range	40–190	40–200		NS

Variable	No	%	No	%	Test	P
Level
L1-2	4	8	2	4
L2-3	4	8	3	6
L3-4	6	16	8	16	Yates	0.82
L4-5	25	50	23	46		NS
L5-S1	11	22	14	28
Post-operative discitis
No	48	96	46	92	Fisher	0.68
Yes	2	4	4	8		NS
Symptoms
Backache	2	4	4	8	Fisher	0.68 NS
Spasm	2	4	4	8	Fisher	0.68 NS
Pain	1	2	3	6	Fisher	0.62 NS
Radiculopathy	1	2	2	4	Fisher	0.99 NS
Time: Mean ± SD	12 ± 5.66	13.75 ± 5.44	t = 0.37	0.73 NS
Lab:			t
ESR: Mean ± SD	82.5 ± 9.95	80 ± 9.83	0.33	0.76 NS
CRP Mean ± SD	34 ± 4.24	38.25 ± 4.11	1.18	0.30 NS
WBCs: Mean ± SD	17.5 ± 1.13	17.1 ± 1.41	0.34	0.75 NS

This table shows that there was no statistical significance difference between the studied groups in operation time, blood loss or level. There was an increase in frequency of post-operative discitis among Group II compared to Group I but without statistical significance difference. Also there was no statistical significance difference between the studied groups in symptoms, time of presentation or laboratory findings of discitis cases
SD: Stander deviation, t: independent t test, χ²: Chi square test, Fisher: Fisher exact test
Yates: Yates correction chi square test, NS: Non significant (P > 0.05)