Surgical management and prognostic factors of spinal metastatic tumors

Egyptian Journal of Neurosurgery

Table 8 Ninth month postoperative outcome (Klekampe score improvement and survival)

	Klekampe score improvement			Survival
	No	%	p	No	%	p^*
Age			0.05			0.07
≤50 years	10/18	56		16/18	89
> 50 years	34/52	65		42/52	81
Sex			0.05			0.05
Male	26/44	58		38/44	86
Female	18/26	69		20/26	77
Clinical			0.001			0.01
Back pain	40/70	57		58/70	83
Paresis	28/38	74		34/38	89
Plegia	2/12	17		4/12	33
Sensory	36/52	67		40/52	77
Sphincter	8/32	25		20/32	63
Duration before surgery			0.001			0.03
<1 week duration	20/24	83		22/24	92
>1 week–1 month	16/26	62		24/26	92
>1 month duration	8/20	40		12/20	60
Preoperative Klekampe score			0.001			0.03
15–19/20	24/26	92		26/26	100
10–14/20	9/12	75		10/12	83
0–9/20	11/32	34		22/32	69
Level			0.05			0.01
Cervical and cervicodorsal junction	8/12	67		8/12	67
Dorsal	26/40	65		36/40	90
Lumbar	6/10	60		10/10	100
Dorsolumber	4/8	50		4/8	50
Extension			0.01			0.01
One vertebra	10/16	63		16/16	100
2–3 vertebrae	32/44	73		36/44	82
> 3 vertebrae	2/10	20		6/10	60
Location to dura			0.01			0.01
Extradural	41/62	66		52/62	84
Intramedullary	1/2	50		1/2	50
Intradural-extramedullary	2/6	33		5/6	84
Resection			0.02			0.02
Gross total	12/16	75		16/16	100
Subtotal	18/24	75		20/24	83
Partial	14/30	47		22/30	73
Instrumentation			0.6			0.05
Yes	24/38	63		34/38	89
No	20/32	63		24/32	75
Duration between primary tumor and spinal metastasis diagnosis			0.01			0.07
n = 36
≤ 1 year	16/24	66.7		22/24	92
> 1 year	12/12	100		12/12	100
Histopathology			0.03			0.001
Lymphoma	12/16	75		14/16	88
Hepatocellular carcinoma	4/10	40		6/10	60
Thyroid carcinoma	6/8	75		8/8	100
Breast carcinoma	4/8	50		6/8	75
Prostatic carcinoma	6/8	75		8/8	100
Cancer bladder	4/6	66.7		5/6	83
Lung carcinoma	1/4	25		4/4	100
Nasopharyngeal carcinoma	2/4	50		2/4	50
Multiple myelomas	4/4	100		4/4	100
Ependymoma	1/2	50		1/2	50