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Table 4 Intracranial and cerebral perfusion pressure changes and excursions in the studied groups (mmHg)

From: The effect of dexmedetomidine versus propofol in traumatic brain injury: evaluation of some hemodynamic and intracranial pressure changes

  Propofol group (n = 20) DEX group (n = 20) Mixed group (n = 20) p value
ICP
Baseline 15.4 ± 3.4 15.7 ± 2.9 15.8 ± 2.6 0.931
 After 2 h 14.7 ± 2.9 14.4 ± 2.8 14.1 ± 2.3 0.787
 After 4 h 13.4 ± 2.1 13.7 ± 3 13.1 ± 1.9 0.703
 After 8 h 13 ± 2.6 12.6 ± 3.5 12.1 ± 2.7 0.673
 After 12 h 12.3 ± 3.4 11.9 ± 4.2 11.5 ± 3.9 0.831
 After 24 h 11.8 ± 4.5 11.1 ± 5.5 10.8 ± 5 0.811
 After 36 h 12 ± 3.5 11.6 ± 4.4 11.2 ± 3.9 0.797
After 48 h 11.8 ± 4 11.2 ± 4.8 11 ± 4.5 0.842
CPP
 Baseline 86 ± 5.54 86.85 ± 6.25 87.3 ± 5.41 0.769
 After 2 h 89.05 ± 4.85 90.3 ± 5.65 90.75 ± 6.93 0.640
 After 4 h 89.35 ± 4.74 89.15 ± 6.16 90.95 ± 6.13 0.555
 After 8 h 89.05 ± 6.92 89.1 ± 7.61 91.35 ± 6.93 0.514
 After 12 h 89.55 ± 5.28 91.1 ± 5.56 90.8 ± 7 0.688
 After 24 h 88.75 ± 7.74 90.6 ± 6.2 91.45 ± 7.73 0.489
 After 36 h 88.1 ± 7.59 88.65 ± 6.44 90.1 ± 9.36 0.711
 After 48 h 87.65 ± 9.73 88.8 ± 7.61 90.3 ± 10.15 0.663
Intracranial pressure excursions, number of patients (percentage) 6 (30%) 7 (35%) 5 (25%) 0.839
Cerebral perfusion pressure excursion, number of patients (percentages) 7 (35%) 5 (25%) 2 (10%) 0.192
  1. ICP excursions > 20 mmHg. CPP excursion < 50 mmHg