Skip to main content

Table 4 Intracranial and cerebral perfusion pressure changes and excursions in the studied groups (mmHg)

From: The effect of dexmedetomidine versus propofol in traumatic brain injury: evaluation of some hemodynamic and intracranial pressure changes

 

Propofol group (n = 20)

DEX group (n = 20)

Mixed group (n = 20)

p value

ICP

Baseline

15.4 ± 3.4

15.7 ± 2.9

15.8 ± 2.6

0.931

 After 2 h

14.7 ± 2.9

14.4 ± 2.8

14.1 ± 2.3

0.787

 After 4 h

13.4 ± 2.1

13.7 ± 3

13.1 ± 1.9

0.703

 After 8 h

13 ± 2.6

12.6 ± 3.5

12.1 ± 2.7

0.673

 After 12 h

12.3 ± 3.4

11.9 ± 4.2

11.5 ± 3.9

0.831

 After 24 h

11.8 ± 4.5

11.1 ± 5.5

10.8 ± 5

0.811

 After 36 h

12 ± 3.5

11.6 ± 4.4

11.2 ± 3.9

0.797

After 48 h

11.8 ± 4

11.2 ± 4.8

11 ± 4.5

0.842

CPP

 Baseline

86 ± 5.54

86.85 ± 6.25

87.3 ± 5.41

0.769

 After 2 h

89.05 ± 4.85

90.3 ± 5.65

90.75 ± 6.93

0.640

 After 4 h

89.35 ± 4.74

89.15 ± 6.16

90.95 ± 6.13

0.555

 After 8 h

89.05 ± 6.92

89.1 ± 7.61

91.35 ± 6.93

0.514

 After 12 h

89.55 ± 5.28

91.1 ± 5.56

90.8 ± 7

0.688

 After 24 h

88.75 ± 7.74

90.6 ± 6.2

91.45 ± 7.73

0.489

 After 36 h

88.1 ± 7.59

88.65 ± 6.44

90.1 ± 9.36

0.711

 After 48 h

87.65 ± 9.73

88.8 ± 7.61

90.3 ± 10.15

0.663

Intracranial pressure excursions, number of patients (percentage)

6 (30%)

7 (35%)

5 (25%)

0.839

Cerebral perfusion pressure excursion, number of patients (percentages)

7 (35%)

5 (25%)

2 (10%)

0.192

  1. ICP excursions > 20 mmHg. CPP excursion < 50 mmHg